INTEGRA Biosciences and Parse Biosciences have teamed up to automate single cell RNA sequencing (scRNA-seq) using the ASSIST PLUS pipetting robot. This collaboration integrates Parse Biosciences’ Evercode™ combinatorial barcoding technology with INTEGRA’s liquid handling expertise to create a more efficient and standardized sequencing process. The result is a faster, more reproducible workflow that benefits academic and industry laboratories alike.

Parse Biosciences, based in Seattle, Washington, specializes in developing advanced tools for large-scale scRNA-seq. Their proprietary Evercode technology allows for the preparation and sequencing of up to a million cells or nuclei simultaneously, using a unique labeling method that eliminates the need for individual cell isolation. By merging this technology with INTEGRA’s sophisticated liquid handling systems, the partnership sets a new benchmark for single cell RNA sequencing, fostering rapid scientific progress.

This collaboration was initiated to tackle common obstacles in the field, such as time-consuming manual workflows and the high costs associated with specialized equipment. Automating the Evercode technology on the ASSIST PLUS pipetting robot, which features the D-ONE single channel pipetting module and an 8-channel VIAFLO lightweight electronic pipette, offers a user-friendly and cost-effective sequencing workflow. This automation reduces hands-on time by 75% and cuts manual pipetting steps by 85%, significantly reducing the workload for lab staff.

scRNA-seq is crucial for advancing knowledge and developing new therapies in areas like developmental biology, neurology, diabetes, cardiovascular disease, and cancer. By making advanced sequencing technologies more efficient and affordable, this partnership opens up new opportunities for research institutions to engage in groundbreaking scientific discoveries. As more labs adopt this automated scRNA-seq solution, it promises to drive faster and more reproducible breakthroughs in understanding complex biological systems and developing innovative treatments for various diseases.

In summary, the integration of Parse Biosciences’ scalable Evercode technology with INTEGRA’s liquid handling expertise not only streamlines sequencing workflows but also enhances the overall efficiency and accessibility of single cell RNA sequencing, pushing the boundaries of scientific research and discovery.